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Probability of heterozygosity at different FXI levels(A) FXI plasma levels exhibit a leptokurtic distribution as compared to platokurtic distribution type of FXII (levels of FXI and FXII from patients admitted to the University Medical Center Mainz from 2012 to 2018; values were limited to patients for which both FXI and FXII assays were performed and extremes (levels ≥150% and ≤ 50%) have. These FXI-related proteins were enriched in immune pathways related to causes of thrombo-inflammation, extracellular matrix interaction, lipid metabolism, and apoptosis. Figure 1. Advance Charge Rs.